Posted on
August 29, 2022

Top 10 VC Investors in Boston

Maximilian Fleitmann
Co-Founder @ BaseTemplates
👉 Full List of 7000+ VC investors - Download now!

Today we're going to discuss the top venture capital firms in Boston. If you're not familiar with the nation's startup network, a good place to start is Boston. Many of the most innovative companies can be found here and VC's are no exception. Below I'll delve into Boston's investment landscape, then list my thoughts on the top ten VCs in Boston.

This article is part of a series where we present you the best Venture Capital firms across different cities and countries. Here you can view the rankings for Philadelphia, New York and San Jose.

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Top Venture Capital Firms in Boston

1. Battery Ventures

Battery Ventures VC - Boston

Battery Ventures is a venture capital firm with offices in Boston, Silicon Valley, and Israel. Battery invests in potentially cutting-edge, category-defining businesses in markets including application software, IT infrastructure technologies, consumer-internet and mobile services, and industrial technologies.


Founded: 1983

Total fund size: $17B

Battery Ventures's most notable exits include Coinbase, Wayfair, and Glassdoor.

2. Polaris Partners

Polaris Partners VC - Boston

Polaris Partners has over 20-year history partnering with repeat entrepreneurs and innovators who are improving the way people live and work. The multibillion-dollar firm invests in healthcare and technology companies across all stages, from founding to profitable growth. Polaris has offices in Boston and San Francisco.

Polaris Partners wasfounded in 1996 and is headquartered in Boston, Massachusetts.


Founded: 1996

Total fund size: $4B

Polaris Partners's most notable exits include Gossamer Bio, Syros Pharmaceuticals, and Neuronetics.

3. Summit Partners

Summit Partners VC - Boston

Summit Partners is an investment firm that is currently investing in to growth equity, fixed income, and public equity opportunities. Summit has invested in more than 460 companies in technology, healthcare, life sciences, and other growth industries. These companies have completed more than 140 public equity offerings, and more than 180 strategic mergers and sales.

Summit Partners enhances the value of these companies through infrastructure development, executive and board recruiting, and strategic and operational advice. The firm also brings extensive experience in helping companies navigate the complex process of public offerings or strategic sales and mergers.

Summit Partners was founded in 1984 and headquartered in Boston, Massachusetts.


Founded: 1984

Total fund size: $35B

Summit Partners's most notable exits include Uber, Infor, and Markforged.

4. Flybridge

Flybridge VC - Boston

Flybridge is a seed-stage VC investing with entrepreneurs to leverage the power of the community. It prefers to invest in computer hardware, software, SaaS, and big data sectors. Founded in 2002, the company is headquartered in Boston, Massachusetts.


Founded: 2002

Total fund size: $859M

Flybridge's most notable exits include MongoDB, DraftKings, and Bulletin.

5. SV Health Investors

SV Health Investors VC - Boston

SV Health Investors, formerly SV Life Sciences, is a leading healthcare and life sciences venture capital and growth equity firm.

Their goal is to transform healthcare – one investment at a time – by supporting the entrepreneurs who create and build breakthrough companies and treatments.

With over $2 billion in capital under management in seven private healthcare funds, a 20-year track record in the US and Europe and offices in Boston, San Francisco and London, SV Health Investors drives game-changing innovation.


Founded: 1993

Total fund size: $2B

SV Health Investors's most notable exits include AvidXchange, IVERIC bio, and X4 Pharmaceuticals.

6. RA Capital Management

RA Capital Management VC - Boston

RA Capital Management is an investment advisor based in Boston specializing in the life-sciences and drug development sectors. Their team has been investing since 2002 and is comprised of professionals with training in biology, chemistry, and medicine and also has industry and business development experience at the executive and board levels. They invest in companies with promising technologies and products. Their approach is to achieve a superior understanding of data, experimental/trial design, regulatory process, and commercial potential. When appropriate, they can offer their portfolio companies leads on in-licensing opportunities and strategic partnerships, as well as insight into the demands of the public markets.


Founded: 2001

Total fund size: $2B

RA Capital Management's most notable exits include Bristol Myers Squibb, Novavax, and ViaCyte.

7. Massachusetts Clean Energy Center

Massachusetts Clean Energy Center VC - Boston

The Massachusetts Clean Energy Center (MassCEC) is dedicated to accelerating the success of clean energy development and implementation—while creating high-quality jobs and long-term economic growth in Massachusetts. MassCEC is the first state agency in the nation dedicated solely to facilitating the development of the clean energy industry. We are led by people who bring knowledge, experience and an entrepreneurial attitude to help clean energy companies take full advantage of all the state’s unique assets, to help accelerate the development of renewable energy generation projects, and to help develop a workforce that is ready to roll up its sleeves to ensure Massachusetts’ place as a national and global clean energy hub.


Founded: 2008

Massachusetts Clean Energy Center's most notable exits include Tesla, General Electric, and SES.

8. Wellington Management

Wellington Management VC - Boston

Wellington Management focuses on investment management. The company applies its full resources to meet the needs of the institutional clients they serve. Their investment approaches span the global equity, fixed income, currency, commodity, and alternatives markets. They also offer asset allocation, multi-manager, and specialty approaches.

It was founded in 1928 and headquartered in Boston, Massachusetts.


Founded: 1933

Total fund size: $393M

Wellington Management's most notable exits include Coinbase, Uber, and DocuSign.

9. .406 Ventures

.406 Ventures VC - Boston

.406 Ventures is an early-stage venture capital firm that invests in innovative Information Technology and services companies founded by the finest entrepreneurs. They are a veteran team of industry entrepreneurs, operators and investors who apply real world experience, deep industry knowledge and networks, and strong company-building skills to create value for our entrepreneurs and investing partners.

.406 Ventures typically are the lead, first institutional investor in early-stage and de novo investments in market-changing IT Security and Infrastructure, Technology-Enabled Business Services, and Next-Generation Software companies.


Founded: 2005

Total fund size: $853M

.406 Ventures's most notable exits include Compass, Veracode, and Kaltura.

10. HLM Venture Partners

 HLM Venture Partners VC - Boston

HLM Venture Partners is a proven, successful venture capital health care investor. Over 60 privately held health care companies have benefited from their expertise, resources and commitment. Emerging health care companies can be confident that HLM Venture Partners' longevity, integrity and reputation will be invaluable assets as they work together to transform their innovative ideas into market-leading businesses.


Founded: 1983

Total fund size: $164M

HLM Venture Partners's most notable exits include Tandem Diabetes Care, Welltok, and Change Healthcare.

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